Willie Peijnenburg

Name

Dr. Willie Peijnenburg

Institute


Rijksinstituut voor Volksgezondheid en Milieu

Postal addresse

RIVM – Laboratory for Ecological Risk Assessment
PO Box 1
Anthonie van Leeuwenhoeklaan 9
3720 BA Bilthoven
The Netherlands

Phone
Phone: +31-30-2743129
Mobile: +31-6-18472405
Fax: +31-30-2744413
Web
Homepage: http://www.rivm.nl
eMail: willie.peijnenburg@rivm.nl
About

Current research interests
- Implementation of bioavailability of heavy metals in risk assessment procedures. The aim of this research is to develop methodologies for assessing soil-type and water-type specific heavy metal standards. Models are developed and validated that combine chemical insights in the area of metal speciation, with biological insights regarding uptake of metals as influenced by compartment-specific and organism-specific factors.
- Development and application of quantitative structureactivity relationships (QSARs) for the estimation of both physicalchemical properties and transformation rates of chemical substances in the environment, with the aim of using these QSARs in models for ecological risk assessment.
- Biotic and abiotic transformation processes of chemical substances in natural ecosystems: development of methods for extrapolating data obtained in laboratory settings to realistic field conditions.
- Fate and effects of organic and inorganic nanomaterials in the environment: fate studies as affected by interactions with biotic and abiotic matrices, and effect studies on aquatic and benthic organisms following assessment of the bioavailable form of the nanomaterials.

Additional:
- Editor Environmental Chemistry of ‘Environmental Toxicology and Chemistry’
- Editor-in-Chief ‘Journal of Soils and Sediments’
- Editor ‘Bulletin Chemical Society Ethiopia’
- Editor newly established open access journal ‘Environmental Sciences’
- Member Editorial Board “Environmental Pollution”
- Member Editorial Board “Environmental Sciences”
- Member Editorial Board “Journal of Safety and Environment”
- Secretary IUPAC Commission on Soil and Water Chemistry
- Secretary of the IUPAC Division on Chemistry and the Environment
- Member of the board of the Section on Environmental Chemistry of the Dutch Royal Chemical Society
- Member of the Peer Review Panel of the Voluntary EU Risk Assessment Reports (VRARs) copper and nickel.
- Member of the Review Panel of Canadian Research Programme “Metals In The Human Environment” (MITHE).
- Member of the Review Panel of the Research Programme on Water Management in Qatar.
- Project leader of various national and international projects in the fields of environmental risk assessment and implementation of the Water Framework Directive, amongst others to allow new EU member states to conform to the requirements of the acquis communautaire.
- Member of the Founding Steering Committee of the Nano Advisory group of SETAC (leader of Work Stream “Toxicokinetics/bioconcentration (ADME)”).

Management activities
- Project manager of various multi-disciplinary projects commissioned by the Dutch Ministry of spatial planning and the environment (VROM): 1990 – 2008. Average annual budget 5 kEuro, topics vary from chemical risk assessment till the implementation of the Water Framework Directive and the projects involve various expertise centres within RIVM and outside RIVM.
- Project manager of EU-funded projects within EU-Research Frameworks V and VI: 1990 – 2008. Average annual budget: 15 kEuro. Currently involved in the EU-funded projects NORMAN, OSIRIS, NOMIRACLE, MODELKEY, ECO (Marie-Curie Programme, funded with 2 PhD students).
- Project coordinator of CADASTER, a so-called medium-sized project with 9 international partners and an overall budget of 4 mEuro. The CADASTER proposal was selected by the EU (DG Research) out of a pool of over 700 project proposals as the sole project of choice within the first call for proposals of the 7th EU Research Framework, to support the implementation of the new chemicals legislation in Europe - REACH.
- Project manager of various projects commissioned by international organizations like NATO, EEA and OECD, as well as projects commissioned by industry, and projects granted within the EU-MATRA and EU-TWINNING programmes (1995 - 2008). All projects are carried out within a multi-disciplinary setting project and have in common that they are granted following peer review and involve international competition. Budgets vary from 100 till 500 kEuro.

Academic activities
- Lecturer in various bachelor and master courses at Wageningen University (soil hygiene), UvA (Environmental Quality; QSARs in Environmental Sciences), University Utrecht, Radboud University Nijmegen, University of Leiden (course Environmental Processes), University of Besançon, Dalian University of Technology (China – Environmental Processes), Saxion Hogeschool (Capita Selecta course and course on environmental risk assessment), Hogeschool Utrecht (Environmental Chemistry), IHE Delft (annual course on Environmental Hygiene).
- Teaching environmental chemistry, multimedia fate modeling, ecotoxicology, effect assessment in national and international (France, Canada, USA, Thailand) post-academic training courses, including Post-doctorate course Toxicology under the supervision of Dr. Hermens (University Utrecht), Dr. Van Gestel (VU, Amsterdam), and Dr. Murk (Wageningen University).
- Member of over 10 National and International Ph.D. committees (2000 – 2008) at universities in the Netherlands (Utrecht, Wageningen, VU, UvA), France (Besançon), Czech Republic (Brno), United States (Delaware) and Canada (University of Toronto).
- Supervisor of various bachelor and master students of national and international universities, universities of applied sciences (“hogescholen”), and the Open University: graduation assignments as well as assignments to improve general skills and/or laboratory skills. Currently: (co-)supervisor of 8 bachelor and master students from the Netherlands, USA, China, Spain.
- Invited lecturer at various international conferences, including the conferences series on QSARs (biennial conference), ICOBTE (International Conference On the Biogeochemistry of Trace Elements; biennial conference), ISEST (International Symposium on Environmental Science and Technology) and SETAC (biannual conferences).
- Invited lecturer at national and international workshops.
- Session chairman/moderator at various national and international workshops and conferences.
- Co-organizer of two one-week conferences on Environmental Biodegradation Processes (Dubrovnik, Croatia) and Environmental Risk Assessment (Bangkok, Thailand).

Curriculum Vitae

Education
1971-1977 Secondary school: Jacob Roelands Lyceum, Boxtel
1977-1984 Eindhoven University of Technology. Graduation in February 1984; Department of Organic Chemistry. Topic of thesis: experimental and theoretical study on the occurrence of photochemically initiated sigmatropic rearrangements.
1984-1988 Eindhoven University of Technology, Ph.D. in Chemical Engineering, 1988. Thesis Title: "An Experimental and Quantumchemical Study on the Mechanism and Stereochemistry of Photochemical [1,3] Sigmatropic Shifts". The Ph.D. study was directed on the various factors that control the mechanism and the stereochemistry of photochemical [1,3]-OH shifts in some newly developed model systems. Promotor: Prof. Dr. Henk Buck.

Positions
1988-1991 Junior Researcher, National Institute of Public Health and Environmental Protection (RIVM); Laboratory for Ecotoxicology, environmental Chemistry and Drinking Water, Bilthoven, The Netherlands.
1991-1995 Senior Researcher, National Institute of Public Health and Environmental Protection (RIVM); Laboratory for Ecotoxicology, Bilthoven, The Netherlands.
1995-2001 Senior Researcher/Project Manager, Laboratory for Ecotoxicology, National Institute of Public Health and Environmental Protection (RIVM), Bilthoven, The Netherlands.
2001 - Project Manager/Scientific co-ordinator Laboratory for Ecological Risk Assessment, National Institute of Public Health and Environmental Protection (RIVM), Bilthoven, The Netherlands.

Experience
1988-1992 Organic chemistry. Instrumental organic analyses, synthetic organic chemistry, photochemistry.
1992-1998 Environmental organic chemistry. Fate and behaviour of organic contaminants in water/soil/sediment.
1998- Metal bioavailability: modeling fate and effects of metals in water/ sediment/soil.
1995- Involved as expert in risk assessments and development of risk assessment methodologies within the framework of the EU-risk assessment of existing chemicals.
1990- Project manager: projects within EU-Research Frameworks V and VI, various multi-disciplinary projects commissioned by the Dutch Ministry for the Environment, projects commissioned by international organizations like NATO, EEA and OECD, projects commissioned by industry, and projects granted within the EU-MATRA and –TWINNING programmes.
2008- Coordinator of EU-Research Framework 7 project CADASTER (CAse studies on the Development and Application of in-Silico Techniques for Environmental hazard and Risk assessment), commissioned by Directorate I (Environment) of the Research Directorate of the European Commission.
1988- Teaching. Teaching environmental chemistry, multimedia fate modeling and effect assessment in national and international post-academic training courses.
2000- Member of over 10 National and International Ph.D. committees.

List of publications

Peer reviewed publications
1. W. Peijnenburg, G. Dormans, G. Bezemer and H. Buck. The conformational controlled stereo and regioselective synthesis of cyclopropane derivatives of 8hydroxygermacrene B. Tetrahedron, 40: 49594962, 1984.
2. G. Dormans, W. Peijnenburg and H. Buck. A nonWoodward and Hoffmann reaction path for photochemical sigmatropic rearrangements. J. Molec. Struct. (Theochem), 119: 367378, 1985.
3. W. Peijnenburg and H. Buck. The effects of substituents and solvent polarity on photochemical [1,3] sigmatropic shifts. Experimental evidence in favour of the occurrence of sudden polarization in acyclic alkenes. Tetrahedron, 44: 49274940, 1988.
4. W. Peijnenburg. An experimental and quantumchemical study on the mechanism and stereochemistry of photochemical [1,3] sigmatropic shifts. Thesis Eindhoven University of Technology, June 1988.
5. W. Peijnenburg. The use of quantitative structure activity relationships for predicting rates of environmental hydrolysis processes. Pure Appl. Chem., 63: 1667-1676, 1991.
6. W. Peijnenburg, M. 't Hart, H. den Hollander, D. van de Meent, H. Verboom and N. Wolfe. Reductive transformations of halogenated aromatic hydrocarbons in anaerobic water-sediment systems: kinetics, mechanisms and products. Environ. Toxicol. Chem., 11: 289-300, 1992.
7. W. Peijnenburg, M. 't Hart, H. den Hollander, D. van de Meent, H. Verboom and N. Wolfe. QSARs for predicting reductive transformation rate constants of halogenated aromatic hydrocarbons in anoxic sediment systems. Environ. Toxicol. Chem., 11: 301-314, 1992.
8. W. Peijnenburg, K. de Beer, M. de Haan, H. den Hollander, M. Stegeman and H. Verboom. The development of a structure-reactivity relationship for the photohydrolysis of substituted aromatic halides. Environ. Sci. Technol., 26: 2116-2121, 1992.
9. T. Vermeire, A. v. Iersel, F. de Leeuw, W. Peijnenburg, P. van de Poel, R. Taalman and C. Toet. Initial assessment of the hazards and risks of new chemicals to man and the environment. Sci. Total Environ., supplement 1993, 1597-1615, 1993.
10. W. Peijnenburg, K. de Beer, H. den Hollander, M. Stegeman and H. Verboom. Kinetics, products, mechanisms and QSARs for the hydrolytic transformation of aromatic nitriles in anaerobic sediment slurries. Environ. Toxicol. Chem., 12: 1149-1161, 1993.
11. W. Peijnenburg. Structure-activity relationships for biodegradation, a critical review. Pure Appl. Chem., 66: 1931-1941, 1994.
12. E. Rorije, M. van Wezel and W. Peijnenburg. On the use of backpropagation neural networks in modeling environmental degradation. SAR QSAR Environ. Res., 4: 219-236, 1995.
13. J. Hermens, S. Balaz, J. Damborský, W. Karcher, M. Müller, W. Peijnenburg, A. Sabljic and M. Sjöström. Assessment of QSARs for predicting fate and effects of chemicals in the environment – an international project. SAR QSAR Environ. Res., 3: 223-236, 1995.
14. E. Rorije, H. Langenberg, J. Richter and W. Peijnenburg. Modeling Reductive Dehalogenation with Quantum Chemically Derived Descriptors. SAR QSAR Environ. Res., 4: 237-252, 1995.
15. H. Langenberg, E. Rorije and W. Peijnenburg. On the reliability and usefulness of existing QSBR's for risk assessment and priority setting. SAR QSAR Environ. Res., 5: 1-16, 1996.
16. E. Rorije and W. Peijnenburg. QSARs for oxidation of phenols in the aqueous environment, suitable for risk assessment. J. Chemometrics, 10: 79-93, 1996.
17. L. Eriksson, H. Verboom and W. Peijnenburg. Multivariate QSAR modelling of the rate of reductive dehalogenation of haloalkanes. J. Chemometrics, 10: 483-492, 1996.
18. S.Z. Lee, H.E. Allen, C.P. Huang, D.L. Sparks, P.F. Sanders and W.J.G.M. Peijnenburg. Predicting soil-water partitioning coefficients for cadmium. Environ. Sci. Technol., 30: 3418-3424, 1996.
19. J. Struijs, D. van de Meent, W. Peijnenburg, M. van den Hoop and T. Crommentuijn. Added risk approach to derive maximum permissible concentrations for heavy metals. Ecotoxicol. Environ. Safety, 37: 112-118, 1997.
20. W. Peijnenburg, L. Posthuma, H. Eijsackers and H. Allen. A conceptual framework for implementation of bioavailability of metals for environmental management purposes. Ecotoxicol. Environ. Safety, 37: 163-172, 1997.
21. R. Janssen, W. Peijnenburg and M. van den Hoop. Equilibrium partitioning of heavy metals in Dutch soils. I. Relationships between metal partition coefficients and soil characteristics. Environ. Toxicol. Chem., 16: 2470-2478, 1997.
22. R. Janssen, L. Posthuma, R. Baerselman, H. den Hollander, R. van Veen and W. Peijnenburg. Equilibrium partitioning of heavy metals in Dutch soils. II. Prediction of metal accumulation in earthworms. Environ. Toxicol. Chem., 16: 2479-2488, 1997.
23. W. Peijnenburg, L. Eriksson, A. de Groot, M. Sjöström and H. Verboom. The kinetics of reductive dehalogenation of a set of halogenated aliphatic hydrocarbons in anaerobic sediment slurries. Environ. Science Poll. Research, 5: 12-16, 1998.
24. E. Rorije, W. Peijnenburg and G. Klopman. Structural requirements for anaerobic biodegradation of organic chemicals: a fragment model analysis. Environ. Toxicol. Chem., 17: 1943-1950, 1998.
25. J. Chen, W. Peijnenburg and L. Wang. Using PM3 Hamiltonian, factor analysis and regression analysis in developing quantitative structure-property relationships for the photohydrolysis of substituted aromatic halides. Chemosphere, 36: 2833-2853, 1998.
26. J. Chen, W. Peijnenburg, X. Quan, Y. Zhao, D. Xue and F. Yang. The application of quantum chemical and statistical techniques in developing quantitative structure-property relationships for the photohydrolysis quantum yields of substituted aromatic halides. Chemosphere, 37: 1169-1186, 1998.
27. H. Loonen, F. Lindgren, B. Hansen, W. Karcher, J. Niemela, K. Hiromatsu, M. Takatsuki, W. Peijnenburg, E. Rorije and J. Struijs. Prediction of biodegradability from chemical structure: modeling of ready bio-degradation test data. Environ. Toxicol. Chem., 18: 1763-1768, 1999.
28. E. Rorije, H. Loonen, M. Müller, G. Klopman and W. Peijnenburg. Evaluation and application of models for the prediction of ready biodegradability in the MITI-I test. Chemosphere, 38: 1409-1417, 1999.
29. W. Peijnenburg, L. Posthuma, P. Zweers, R. Baerselman, A. de Groot, R. Van Veen and D. Jager. Prediction of metal bioavailability in Dutch field soils for the oligochaete Enchytraeus crypticus. Ecotoxicol. Environ. Saf., 40: 170-186, 1999.
30. W. Peijnenburg, L. Posthuma, P. Zweers, R. Baerselman, A. de Groot, R. Van Veen and D. Jager. Relating environmental availability to bioavailability: soil-type dependent metal accumulation in the oligochaete Eisenia andrei. Ecotoxicol. Environ. Saf., 44: 294-310, 1999.
31. L. Klasinc, W. Peijnenburg, A. Sabljić and J. Slanina (volume editors). Degradation processes in the Environment. Chemosphere, 38: 1189-1468, 1999.
32. S. Wiegman, P. Van Vlaardingen, S. van Beusekom, W. Peijnenburg, M. Kraak and W. Admiraal. Photokinetics of azaarenes and toxicity of phototransformation products to the marine diatom Phaedactylum tricornutum. Environ. Sci. Technol., 33: 4256-4262, 1999.
33. J. Chen, W. Peijnenburg, X. Quan and F. Yang. Quantitative structure-property relationships for direct photolysis quantum yields of selected polycyclic aromatic hydrocarbons. Science Total Environ., 246: 11-20, 2000.
34. J. Chen, W. Peijnenburg, X. Quan, S. Chen, Y. Zhao and F. Yang. The use of PLS algorithms and quantum chemical parameters derived from PM3 hamiltonian in QSPR studies on direct photolysis quantum yields of substituted aromatic halides. Chemosphere, 40: 1319-1326, 2000.
35. W. Peijnenburg, R. Baerselman, A. de Groot, T. Jager, D. Leenders, L. Posthuma, and R. Van Veen. Quantification of metal bioavailability for Lettuce (Lactuca sativa L) in field soils. Arch. Environ. Contam. Toxicol., 39: 420-430, 2000.
36. A. Sabljić, W.J.G.M. Peijnenburg. Modeling lifetime and degradability of organic compounds in air, soil, and water systems. Pure Appl. Chem., 73: 1331-1348, 2001.
37. J. Chen, X. Quan, Y. Yan , F. Yang and W. Peijnenburg. Quantitative structure-property relationship studies on direct photolysis of selected polycyclic aromatic hydrocarbons in atmospheric aerosol. Chemosphere, 42: 263-270, 2001.
38. J. Chen, X. Quan, F. Yang and W. Peijnenburg. Quantitative structure-property relationships on photodegradation of PCDD/Fs in cuticular waxes of laurel cherry (Prunus Laurocerasus). Science Total Environ., 269: 163-170, 2001.
39. J. Chen, W. Peijnenburg, X. Quan, S. Chen, D. Martens, K.-W. Schramm and A. Kettrup. Is it possible to develop a QSPR model for direct photolysis half-lives of PAHs under irradiation of sunlight? Environ. Poll., 114: 137-143, 2001.
40. J. Chen, X. Quan, W. Peijnenburg and F. Yang. Quantitative structure-property relationships (QSPRs) on direct photolysis quantum yields of PCDDs. Chemosphere, 43: 235-241, 2001.
41. H. Zhao, J. Chen, X. Quan, F. Yang and W. Peijnenburg. Quantitative structure-property relationship study on reductive dehalogenation of selected halogenated aliphatic hydrocarbons in sediment slurries. Chemosphere, 44: 1557-1563, 2001.
42. M. Vijver, T. Jager, L. Posthuma and W. Peijnenburg. The impact of metal pools and soil properties on metal accumulation in Folsomia candida (Collembola). Environ. Toxicol. Chem., 20: 712-720, 2001.
43. M. Vijver, T. Jager, L. Posthuma and W. Peijnenburg. Influences of soil characteristics on metal uptake from soils and mixtures of soils and sediments by the beetle larvae Tenebrio molitor (L.) (Col. Tenebrionidae). Ecotoxicol. Environ. Safety, 54: 277-289, 2003.
44. J. Damborský, E. Rorije, A. Jesenká, Y. Nagata, G. Klopman and W. Peijnenburg. Structure-Specificity Relationships for Haloalkane Dehalogenases. Environ. Toxicol. Chem., 20: 2681-2689, 2001.
45. Heikens, W.J.G.M. Peijnenburg and A.J. Hendriks. Bioaccumulation of heavy metals in terrestrial invertebrates. Environ. Poll., 113: 385-403, 2001.
46. J.K. Saxe, C.A. Impellitteri, W.J.G.M. Peijnenburg and H.E. Allen. Novel model describing trace metal concentrations in the earthworm Eisenia andrei. Environ. Sci. Technol., 35: 4522-4529, 2001.
47. C.A. Impellitteri, Y. Lu, J.K. Saxe, H.E. Allen and W.J.G.M. Peijnenburg. Correlation of the partitioning of dissolved organic matter fractions with the desorption of Cd, Cu, Ni, Pb and Zn from 18 Dutch soils. Environ. Int., 28: 401-410, 2002.
48. W. Peijnenburg, E. Sneller, D. Sijm, J. Lijzen, T. Traas and E. Verbruggen. Implementation of bioavailability in standard setting and risk assessment? J. Soils Sediments, 2: 169-173, 2002.
49. P. van Beelen, E. Verbruggen and W. Peijnenburg. The evaluation of the equilibrium partitioning method using sensitivity distributions of species in water and soil. Chemosphere, 52: 1153-1162, 2003.
50. T. Jager, R. Baerselman, E. Dijkman, A. de Groot, E. Hogendoorn, A. de Jong, J. Kruitbosch, W. Peijnenburg. Availability of polycyclic aromatic hydrocarbons to earthworms (Eisenia andrei, oligochaeta) in field-polluted soils and soil-sediment mixtures. Environ. Toxicol. Chem., 22: 767-775, 2003.
51. S. Baker, M. Herrschen, K. Hund-Rinke, W. Klein, W. Kördel, W. Peijnenburg and C. Rensing. Underlying issues including approaches and information needs in risk assessment. Ecotoxicol. Environ. Safety, 56: 6-19, 2003.
52. R. Fleuren, T. Jager, W. Roelofs, A. de Groot, R. Baerselman and W. Peijnenburg. Feeding behaviour of Eisenia andrei in two different field contaminated soils. Pedobiologia, 47: 670-675, 2003.
53. W. Peijnenburg and T. Jager. Monitoring approaches to assess bioaccessibility and bioavailability of metals: matrix issues. Ecotoxicol. Environ. Safety, 56: 63-77, 2003.
54. H. Egli, M. Dassenakis, H. Garelick, R. van Grieken, W Peijnenburg, L. Klasinc, W. Kördel, N. Priest and T. Tavares. Minimum requirements for reporting analytical data for environmental samples. Pure Appl. Chem., 75: 1097-1106, 2003.
55. W. Peijnenburg, E. Sneller, D. Sijm, J. Lijzen, T. Traas and E. Verbruggen. Implementation of bioavailability in standard setting and risk assessment. Suggestions based on a workshop with emphasis on metals. Environ. Sci., 11: 141-149, 2004.
56. W. Peijnenburg, E. Sneller, D. Sijm, J. Lijzen, T. Traas and E. Verbruggen. Implementation of bioavailability in standard setting and risk assessment. Suggestions based on a workshop with emphasis on metals. Arh. Hig Rada Toksikol., 55: 273-278, 2004.
57. M. Koster, L. Reijnders, N.R. van Oost and W.J.G.M. Peijnenburg. Comparison of the method of diffusive gels in thin films with conventional extraction techniques for evaluating zinc accumulation in plants and isopods. Environ. Poll. 133: 103-116, 2005.
58. M.G. Vijver, C.A.M. van Gestel, R.P. Lanno, N.M. van Straalen and W.J.G.M. Peijnenburg. Internal metal sequestration and its ecotoxicological relevance – a review. Environ. Sci. Technol., 38: 4705-4712, 2004.
59. W. Peijnenburg, A. de Groot, T. Jager and L. Posthuma. Short term ecological risks of depositing contaminated sediment on arable soil. Ecotoxicol. Environ. Safety, 60: 1-14, 2005.
60. A.D. Vethaak, J. Lahr, S.M. Schrap, A.C. Belfroid, G.B.J. Rijs, A. Gerritsen, J. de Boer, A.S. Bulder, G.C.M. Grinwis, R.V. Kuiper, J. Legler, T.A.J. Murk, W. Peijnenburg, H.J.M. Verhaar and P. de Voogt. An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands. Chemosphere, 59: 511-524, 2005.
61. R. Bos, M. Huijbregts and W. Peijnenburg. Soil type-specific environmental quality standards for zinc in Dutch soil. Integr. Environ. Assessm. Managem., 1: 252-258, 2005.
62. A. Sabljić and W. Peijnenburg. Modeling lifetime and degradability of organic compounds in air, soil, and water systems. Angewandte Chemie, 117: 834-845, 2005.
63. N. Steenbergen, F. Iaccino, M. de Winkel, L. Reijnders and W. Peijnenburg. Development of a biotic ligand model and a regression model predicting acute copper toxicity to the earthworm Aporrectodea caliginosa. Environ. Sci. Technol., 39: 5694-5702, 2005.
64. R. Posthumus, T.P. Traas, W. Peijnenburg and E. Hulzebos. External validation of EPIWIN biodegradation models. SAR QSAR Environ. Res., 16: 135-148, 2005.
65. S. Yoshida, Y. Muramatsu and W. Peijnenburg. Multi-element analysis of earthworms for radioecology and ecotoxicology. Radioprotection, Suppl. 1, 40: S491-S495, 2005.
66. M.G. Vijver, C.A.M. van Gestel, N.M. van Straalen, R.P. Lanno and W.J.G.M. Peijnenburg. Biological significance of metals partitioned to subcellular fractions within earthworms (Aporrectodea caliginosa). Environ. Toxicol. Chem., 25, 807-814, 2006.
67. W. Peijnenburg and J. Struijs. Occurrence of phthalate esters in the environment of the Netherlands. Ecotoxicol. Environ. Safety, 63, 204-215, 2006.
68. P. van Vliet, W. Didden, S. van der Zee and W. Peijnenburg. Accumulation of heavy metals by enchytraeids and earthworms in a floodplain. Eur. J. Soil Biol., 42: 117-126, 2006.
69. M. Koster, A. de Groot, M. Vijver and W. Peijnenburg. Copper in the terrestrial environment: verification of a laboratory-derived terrestrial biotic ligand model to predict earthworm mortality with toxicity observed in field soils. Soil Biol. Biochem. 38, 1788-1796, 2006.
70. M.G. Vijver, M. Koster and W.J.G.M. Peijnenburg. Impact of pH on Cu accumulation kinetics in earthworm cytosol. Environ. Sci. Technol. 41, 2255-2260, 2007.
71. K. Veltman, M.A.J. Huijbregts, M.G. Vijver, W.J.G.M. Peijnenburg, P.H.F. Hobbelen, J.E. Koolhaas, C.A.M. van Gestel, P.C.J. van Vliet and A.J. Hendriks. Metal accumulation in the earthworm Lumbricus rubellus. Model predictions compared to field data. Env. Poll. 146, 428-436, 2007.
72. W.J.G.M. Peijnenburg, M. Zablotskaja and M.G. Vijver. Monitoring metals in terrestrial environments within a bioavailability framework and a focus on soil extraction. Ecotoxicol. Environ. Safety. 67, 163-179, 2007.
73. W.J.G.M. Peijnenburg and M.G. Vijver. Metal Specific Interactions at the Interface of Chemistry and Biology. Pure Appl. Chem. 79, 2351-2366, 2007.
74. B.E. Arnold, M.E. Hodson, J. Charnock and W.J.G.M. Peijnenburg. Comparison of Subcellular Partitioning, Distribution, and Internal Speciation of Cu between Cu-Tolerant and Naïve Populations of Dendrodrilus rubidus Savigny. Environ. Sci. Technol. 42: 3900-3905, 2008.
75. F. Gimbert, M.G. Vijver, M. Coeurdassier, R. Scheifler, W.J.G.M. Peijnenburg, P.-M. Badot, A. de Vaufleury. How Subcellular Partitioning Can Help to Understand Heavy Metal Accumulation and Elimination Kinetics in Snails. Environ. Toxicol. Chem., 27, 1284-1292, 2008.
76. M.G. Vijver, A. de Koning, W.J.G.M. Peijnenburg. Uncertainty of water type specific hazardous copper concentrations derived with biotic ligand models. Environ. Toxicol. Chem., 27, 2311-2319, 2008.
77. W. Kördel, W. Peijnenburg, C.L. Klein, G. Kuhnt, B.M. Bussian, B.M. Gawlik. The reference-matrix concept applied to chemical testing of soils. Trends Anal. Chem., 28, 51-63, 2009.
78. S.W.P. Wijnhoven, W.J.G.M. Peijnenburg, C.A. Herberts, W.I. Hagens, A.G. Oomen, E.H.W. Heugens, B. Roszek, J. Bisschops, I. Gosens, D. van de Meent, S. Dekkers; W. de Jong, M. van Zijverden, A.J.A.M. Sips, R.E. Geertsma. Nano-silver - a review of available data and knowledge gaps in human and environmental risk assessment. Nanotoxicology. DOI: 10.1080/17435390902725914. 2009.

Books/book chapters
1. W. Peijnenburg, M. 't Hart, H. den Hollander, D. van de Meent, H. Verboom and N. Wolfe. QSARs for predicting biotic and abiotic transformation rate constants of halogenated hydrocarbons in anoxic sediment systems. Sci. Total Environ., 109/110: 283-300, 1991. Also published in: QSAR in Environmental Toxicology. J. Hermens and A. Opperhuizen (Eds.), Elsevier, Amsterdam, 283-300, 1991.
2. W. Peijnenburg. Some experiences in the Netherlands regarding the presence of xenobiotics in drinking water sources. In: A.J. Dobbs, W.J.G.M. Peijnenburg, T.R. Roberts and M. Waldman (Eds.). Pesticides in surface water, mechanisms of transport and control. Proceedings of the IUPAC workshop, August, Hamburg, 1991. 89-93, 1992.
3. M. van de Berg, D. van de Meent, W. Peijnenburg, D. Sijm and W. Tas. Transport, accumulation and transformation processes. In: C. van Leeuwen and J. Hermens (Eds.). Risk assessment of chemicals. Kluwer, Dordrecht. 37-102, 1995.
4. W. Peijnenburg and J. Damborský (Eds.). Biodegradability Prediction. Kluwer Academic Publishers, Dordrecht/Boston/London, 1997.
5. L. Posthuma, J. Notenboom, A. de Groot and W. Peijnenburg. Soil acidity as a major determinant of zinc partitioning and zinc uptake in two oligochaete worms (Eisenia andrei and Enchytraeus crypticus) exposed in contaminated field soils. In: Sheppard S, Bembridge J, Holmstrup M, Posthuma L (eds) Advances in earthworm ecotoxicology. SETAC Press, Pensacola, FL USA, 111-127, 1998.
6. W. Peijnenburg, A. de Groot and R. van Veen. Experimental and theoretical study on equilibrium partitioning of heavy metals. In: I. Iskandar, M.B. Kirkham (Eds). Trace elements in soil. Bioavailability, flux and transfer. CRC Press, Boca Raton, FL, USA, 91-126, 2001.
7. W. Peijnenburg. Mogelijke verklaringen voor de grote variatie in beschikbaarheid van metalen in landbodems. In: Jaarboek 2002. Sectie Milieuchemie. Koninklijke Nederlandse Chemische Vereniging. 's-Gravenhage: KNCV, 22-26, 2002.
8. W. Peijnenburg, D. Sijm, J. Lijzen, E. Sneller, T. Traas, and E. Verbruggen. Biobeschikbaarheid: hoe kun je dat gebruiken in normstelling en risicobeoordeling? In: Jaarboek 2002. Sectie Milieuchemie. Koninklijke Nederlandse Chemische Vereniging. 's-Gravenhage: KNCV, 12, 2002.
9. W.J.G.M. Peijnenburg. Bioavailability of metals to soil invertebrates. In: H.E. Allen (Ed). Bioavailability of metals in terrestrial ecosystems. SETAC Press, Pennsacola, Fl. 115-142, 2002.
10. W.J.G.M. Peijnenburg. Fate of contaminants in soils. In: P. Doelman, H. Eijsackers (Eds). Vital soil. Function, value and properties. Elsevier, Amsterdam, The Netherlands, 245-280, 2004.
11. D. Sijm, M. Rikken, E. Rorije, T. Traas, M. McLachlan and W. Peijnenburg. Transport, accumulation and transformation processes. In: C. van Leeuwen and T. Vermeire (Eds.). Risk assessment of chemicals – 2nd edition. Spinger, Berlin. 73-158, 2007.
12. W.J.G.M. Peijnenburg, M.G. Vijver, M. Koster. Impact of pH on Cu accumulation kinetics in earthworm cytosol. In: Y. Zhu, N. Lepp, R. Naidu (Eds.). Biogeochemistry of trace elements: environmental protection, remediation and human health. Tsighua University Press, Bei Jing (China), 645-647, 2007.
13. D. de Zwart, A. Warne, V.E. Forbes, W.J.G.M. Peijnenburg, D. van de Meent, D. Matrix and media extrapolation. In: K.R. Solomon, T.C.M. Brock, S.D. Dyer, L. Posthuma, S. Richards, H. Sanderson, P.K. Sibley, P.J. van den Brink, D. de Zwart, (Eds.). Extrapolation practice for ecological effect characterization of chemicals (EXPECT). SETAC Press, Pensacola, FL, 2008.
14. W.J.G.M. Peijnenburg. Phthalates. In: S.E. Jørgensen, B.D. Fath (Editors-in-Chief), Ecotoxicology. Vol. 4 of Encyclopedia of Ecology, 1st edition, Elsevier b.v., Oxford, 2733-2738, 2008.

Reports
1. W. Peijnenburg, H. den Hollander, J. Verboom, D. van de Meent and N. Wolfe. The development of structure-activity relationships for the reduction of halogenated aliphatic hydrocarbons in anaerobic water-sediment systems. RIVM report 718817002, 1989.
2. W. Peijnenburg. Evaluation system new substances: Assessment methodology for transformation rates. RIVM report no. 718708002, 1989.
3. W. Slooff, J. Janus, C. Koning, W. Peijnenburg and J. Ros. Exploratory report phthalates. RIVM report no. 710401001, 1990.
4. D. Jager, T. Vermeire, C. Visser (Eds.). C. Toet, A. de Nijs, P. van der Poel, J. Tuinstra, D. van de Meent, P. van der Zandt, W. Peijnenburg, H. Booij, H. Roelfzema, H. Emans, M. Beek and J. Linders. Uniform beoordelingssysteem stoffen (UBS); tweede prototype. RIVM Report no. 679120002, 1992.
5. T. Vermeire, E. Kroese, G. Meyer, G. Mohn, J. Notenboom, W. Peijnenburg, A. Piersma and C. Roghair. Initial assessment of the hazards and risks of new substances for man and the environment, part II. RIVM report no. 679102018, 1993.
6. E. Rorije, J. Richter and W. Peijnenburg. The use of quantum chemically derived descriptors for QSAR modeling of anaerobic dehalogenation of aromatic compounds. RIVM report no. 719101015, 1994.
7. W. Peijnenburg and W. Karcher. Proceedings of the workshop "Quantitative Structure Activity Relationships for biodegradation" [September 1994, Belgirate, Italy]. RIVM Report 719101021, 1995.
8. R. Janssen, P. Pretorius, W. Peijnenburg and M. van den Hoop. Determination of field-based partition coefficients for heavy metals in Dutch soils and the relationships of these coefficients with soil characteristics. RIVM report no. 719101023, 1996.
9. P. Pretorius, R. Janssen, W. Peijnenburg and M. van den Hoop. Chemical equilibrium modelling of metal partitioning in soils. RIVM report no. 719101024, 1996.
10. W. Peijnenburg, M. van de Hoop. D. van de Meent and J. Struijs. A conceptual basis for dealing with background concentrations and risk levels in deriving environmental quality objectives. RIVM report no. 719101018, 1996.
11. R. Janssen, F. Swartjes, M. van den Hoop and W. Peijnenburg. Evaluatie van het evenwichtspartitieconcept voor zware metalen in bodems en sedimenten. RIVM report no. 719101027, 1996.
12. E. Rorije E, M. Müller and W. Peijnenburg. Prediction of environmental degradation rates for High Production Volume Chemicals (HPVC) using Quantitative Structure-Activity Relationships. RIVM report no. 719101030, 1997.
13. A. de Groot, W. Peijnenburg, M. van den Hoop, R. Ritsema and R.P.M. van Veen. Heavy metals in Dutch field soils: an experimental and theoretical study on equilibrium partitioning. RIVM report no. 607220001, 1998.
14. J. Otte, J. van Grinsven, W. Peijnenburg and A. Tiktak. Determination of field-based sorption isotherms for Cd, Cu, Pb and Zn in Dutch soils. RIVM report no. 711401007, 1999.
15. L. Posthuma, A. de Groot, D. Jager, W. Peijnenburg, R. Baerselman, R.Ritsema, E. van der Velde and R. Franken. Beoordeling van de ecotoxicologische risico’s van de verspreiding van baggerspecie op land, RIVM-rapport 733007006, 1999.
16. W. Peijnenburg, H. den Hollander, R. Luttik, D. van de Meent and D. de Zwart. Ontwikkeling en toepassing van een Milieukwaliteitsindicator Bestrijdingsmiddelen. RIVM report no. 60788002, 2000.
17. M. van den Hoop, W. Peijnenburg, D. Sijm, G. van den Berg, L. van der Heijdt and J. Zwolsman. Acid Volatile Sulfide (AVS) als instrument bij de risicobeoordeling van waterbodems. RIVM report no. 607220003, 2000.
18. M. Rutgers, T. Aldenberg, R. Franken, D. Jager, J. Lijzen, W. Peijnenburg, A. Schouten, T. Traas, D. de Zwart and L. Posthuma. Ecologische risicobeoordeling van verontreinigde (water)bodem – voorstellen ter verbetering van de urgentiesystematiek. RIVM report no. 711701018, 2000.
19. W. Peijnenburg, R. Franken, A. de Groot, E. Hogendoorn, D. Jager, L. Posthuma and R. Ritsema. Ecotoxicologische risico's van de verspreiding van baggerspecie uit regionale wateren op land: Vervolgonderzoek naar de ecologische betekenis van normoverschrijding. RIVM report no. 733007007, 2001.
20. W.J.G.M. Peijnenburg, D.T. Jager, L. Posthuma and D.T.H.M. Sijm. Huidige mogelijkheden en inzichten voor implementatie van metaalbiobeschikbaarheid in de risicobeoordeling van landbodems. RIVM report no. 607220004, 2001.
21. P. van Beelen, E. Verbruggen, W. Peijnenburg. The evaluation of the equilibrium partitioning method using sensitivity distributions of species in water and soil or sediment. RIVM report no. 607220005, 2002.
22. D. Sijm, J. Lijzen, W. Peijnenburg, E. Sneller, T. Traas and E. Verbruggen. Biobeschikbaarheid in beleid ... wat er aan vooraf ging en wat nog komt. Resultaten van een workshop en het beleidsvervolg (Bioavailability in standard setting, results of a workshop). RIVM report 607220006, 2002.
23. E.M. Dirven, P. van Vlaardingen, W. Peijnenburg, D. Sijm and L. Posthuma. Pilotstudie naar toetsing van ecologische relevantie van soorten voor normstelling (Pilot study for assessing the ecological relevance of biotic species used in ecotoxicity testing). RIVM report no. 607220007, 2002.
24. J. Struijs and W. Peijnenburg. Predictions by the multimedia environmental fate model SimpleBox compared to field data: Intermedia concentration ratios of two phthalate esters. RIVM report no. 607220008, 2002.
25. W. Peijnenburg, R. Baerselman, A. de Groot and C. Strien. Biobeschikbaarheid van essentiele metalen voor bodem-organismen: zinktitratie als middel ter bepaling van accumulatie en toxiciteit. RIVM report no. 607220009, 2003.
26. W. Peijnenburg, J. Bogte, H. van Wijnen and A. Wintersen. Towards a European Chemicals Information System: a survey on reported monitoring activities of chemicals in Europe. RIVM report no. 607900001, 2004.
27. A. Schouten et al. Site specific ecological risk assessment. Research with the TRIAD approach: part 3. RIVM report no. 711701036, 2004.
28. P. van Noort et al. Beslissen over bagger op bodem. Deel 2. Onderbouwing stofgedragmodellering en voorspelde landbodemconcentraties na verspreiding bagger op land. RIVM report no. 711701045, 2006.
29. J.J.G. Zwolsman and W.J.G.M. Peijnenburg. 2e-lijnsbeoordeling ecologische risico's in oppervlaktewater. Wat te meten in 2007? KIWA-report no. 06.112, 2006.
30. T. Vermeire et al. Selected Integrated Testing Strategies (ITS) for the risk assessment of chemicals. RIVM report no. 601050001, 2007.
31. W. Peijnenburg. Establishment of a Pesticide Information and Support Centre in Slovakia – Completion report for project PPA04/SK/6/8. Joint report of RIVM, TNO, CTB and Septa Management within the framework of RIVM-project E/607029/01/AA, 2007.
32. J. Struijs, D. van de Meent, W.J.G.M. Peijnenburg, E. Heugens, W. de Jong, W. Hagens, C. de Heer, J. Hofman and E. Roex. Nanodeeltjes in water. RIVM report no. 607030001, 2007.
33. W.J.G.M. Peijnenburg and H.A. den Hollander. Supporting REACH – Development of building blocks of a module for intelligent testing of data-poor organic substances. RIVM report no. 607220011, 2008.
34. H. den Hollander, A. Franco, S. Trapp, W. Peijnenburg. Sorption of polar and ionic compounds - A review of available data and models. OSIRIS report M 3.1.5. Available from the OSIRIS-website: www.osiris.ufz.de. 2008.
35. S. Wijnhoven, C. Herberts, W. Hagens, A. Oomen, E. Heugens, B. Roszek, J. Bisschops, W. Peijnenburg, I. Gosens, D. van de Meent, S. Dekkers, C. de Heer, A. Sips, W. de Jong, M. van Zijverden, R. Geertsma. Nano-silver - A review of available data and knowledge gaps. RIVM report 360003001, 2008.

Professional publications
1. R. Franken, S. van Dijk, W. Peijnenburg and L. Posthuma. Verspreiding van baggerspecie op land. H2O, 14/15: 24-26, 2000.
2. E. Sneller and W. Peijnenburg. Biobeschikbaarheid: (hoe) te gebruiken in normstelling en risicobeoordeling. H2O, 19: 96-97, 2002.
3. W. Peijnenburg, H. den Hollander, D. van de Meent and D. de Zwart. Ontwikkeling en toepassing van een milieukwaliteits-indicator bestrijdingsmiddelen. H2O, 35: 28-30, 2002.
4. P. van Beelen, W. Peijnenburg and G. van de Berg. Is een verbetering van de metaalnormen voor de waterbodems mogelijk? H2O, 36: 29-31, 2003.
5. W. Peijnenburg, D. Sijm, J. Lijzen, T. Traas, E. Verbruggen and E. Sneller. Biobeschikbaarheid: (hoe) kun je dat gebruiken in normstelling en risicobeoordeling? Bodem, 13: 18-20, 2003.
6. T. Breure and W. Peijnenburg. Developments in soil protection in The Netherlands. J. Soils Sedim., 3: 248-249, 2003.
7. W. Peijnenburg, E. Sneller, D. Sijm, J. Lijzen, and T. Traas, E. Verbruggen. Implementation of bioavailability of standard setting and risk assessment. SETAC Globe, 3: 36-38, 2003.
8. W. Peijnenburg and M. Vijver. Predicting toxicity of metals to soil organisms. SETAC Globe, 7: 19-20, 2006.
9. M. Vijver, W. Peijnenburg and A. de Koning. Biotic ligand modellen in lijn met kaderrichtlijn water. H2O, 12: 29-31, 2006.
10. W. Peijnenburg, M. Vijver and A. de Koning. Aanzet voor watertype specifieke risicogrenzen voor metalen in oppervlaktewater. H2O, 17: 35-37, 2007.
11. T. de Nijs, D. de Zwart and W. Peijnenburg. Toxiciteit van het oppervlaktewater blijft een probleem. H2O, 21: 29-31, 2008.